Micro-Bioprocess Engineering
The effective generation of process information represents a major bottleneck in microbial process optimisation. An approach to overcome the necessity of a large number of time- and labour-consuming experiments in shaking flasks and small-scale bioreactors is miniaturisation and parallelisation of stirred-tank reactors along with automation of process management and digitalization of bioprocess development.
Finished research projects
- Miniaturized stirred-tank reactors with LED illumination for photoautotrophic high-throughput bioprocess design
- Automated optimization of microbial protein expression by combining parallel reactor systems in the digitized bioprocess laboratory
- Production of halophilc enzymes using Haloferax volcanii in a stirred-tank bioreactor
- Continuous fermentations in miniaturized stirred-tank reactors
- Micro-dosing device and micro-sensors for pH control in parallel bioreactors
- Reaction engineering studies of butanol fermentation with Clostridium acetobutylicum strains in stirred-tank reactors
- Computational fluid dynamics as a tool for bioreactor characterization
- Small-scale stirred-tank reactors for enzymatic hydrolyses of suspended plant materials
- Parallel reaction engineering analysis of microbial fed-batch processes
- Small-scale stirred tank reactors for the cultivation of microorganisms with varying morphology
- Reaction engineering studies on microbial riboflavin production with small-scale stirred-tank reactors
- Reaction engineering optimisation of parallel reactors for controlled bioprocesses
- Scale-down and parallel operation of a riboflavin production process with Bacillus subtilis
- Miniaturized parallel bioreactors for high-throughput bioprocess design